Is `/dev/urandom` suitable for simulation purpose?

It seems that using plain C in unix-like systems, fread from /dev/urandom is the simplest way to extract high quality random bytes. I need to run a simulation that needs about 10k 32-bit random numbers per second, and it may run for several days. Is /dev/urandom okay to use for this purpose? How is the quality of random bytes from here when the entropy pool is depleted?