Where can I find genuine errors in computers?

I want to write a software that mimic the DNA mutation errors naturally. I can do so using some sort of pseudo-random number generators but it's not elegant and require too much calculations.

I wondering if there is way that I can access some genuine errors from the machine?

I was thinking maybe I need to overclock my CPU and then I will get some errors but I afraid that it will be too much unstable and I will suffer from multiple crashes.

Where do usually computers make mistakes?